Most early studies on 3D genome organization used imaging-based approaches, and the development of the first genomic method to query the 3D genome over two decades ago – chromosome conformation capture – created a massive ripple effect across the field.
Together, spatial genomics and spatial transcriptomics promise to revolutionize both biology and medicine by providing unprecedented insights into the spatial organization of tissues and how fundamental cellular processes are orchestrated in multicellular organisms.
We summarize how the toolkit for charting genome topology
We summarize how the toolkit for charting genome topology
We summarize how the toolkit for charting genome topology
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